Dutch Translational Metabolism Conference 30-31st of May 2024
Hotel de Wageningsche Berg, Wageningen, The Netherlands
| Day 1 | 30th of May, 2024 |
| 10:00 – 10.30 | Registration and coffee |
| 10.30 – 10.45 | Opening remarks |
| Session 1 | |
| 10.45 – 11.05 | Patrick van der Zande (Wageningen University), A#37 Weight cycling modifies the visceral adipose tissue and liver immune landscape without impacting whole-body insulin resistance in mice |
| 11.05 – 11.25 | Fenne Verheijen (Utrecht UMC), A#40 Deciphering a tolerogenic diet; Is glutamate a key nutrient for tolerogenic dendritic cell functionality? |
| 11.25 – 11.45 | Tobias Ackermann (CRUK Scotland Institute), A#1 Paracrine secretion of mono-unsaturated fatty acids prevents ferroptosis in triple-negative breast cancer and reveals selenocysteine synthesis dependency for lung metastasis |
| 11.45 – 12.30 | Keynote speaker: Prof. Luke O’Neill Topic: Immunometabolism Title: A break in mitochondrial endosymbiosis as a basis for inflammatory diseases Trinity College Dublin, Ireland |
| 12.30 – 13.00 | Lunch |
| Session 2 | |
| 13.30 – 13.50 | Evi Koene (Maastricht UMC), A#21 Pharmacological inhibition of fructose metabolism reduces liver fat and improves insulin sensitivity in participants with MASLD |
| 13.50– 14.10 | Jamie van der Vaart (Leiden UMC), A#36 Mitochondrial uncoupling with BAM15 prevents weight gain, lowers plasma cholesterol and attenuates atherosclerosis development in APOE*3-Leiden.CETP mice |
| 14.10 – 14.55 | Keynote speaker: Prof. Bart Deplancke Topic: Adipose biology Title: Deconstructing adipose tissue plasticity, one cell at a time EPFL, Switzerland |
| 14.55 – 15.10 | Sponsor pitches |
| Masterclass & poster presentations | |
| 15.30 – 16.30 | Masterclass – Science Communication Guest speakers: – Martine Kamsma (Nutrition and Health Editor at NRC media) – Jayson & Suzanne (Hosts of “The Struggling Scientists Podcast”) – Eileen Daniels (Science communicator and research advisor in the field of medicine and natural sciences) |
| 16:45 – 17:00 | 6 selected poster pitch presentations Dandan Wu (Amsterdam University) Xiaomeng Zhang (Amsterdam UMC) Ruiqi Xiao (University of Groningen) Anouk Gijbels (Wageningen University) Froukje Vanweert (Maastricht University) Demi Rijlaarsdam (Utrecht University) |
| 17:00 – 18:00 | Poster session 1 |
| 18:15 – 19:15 | Poster session 2 |
| 19:15 –21.00 | Dinner |
| 21.00 – | Evening program: PubQuiz |
| Day 2 | 31st of May, 2024 |
| 7.30 – 8.15 | Boot camp |
| 8.30 – 9.30 | Breakfast |
| Session 3 | |
| 9.30 – 9.50 | Berith Balfoort (Amsterdam UMC), A#2 Altered mitochondrial function in induced pluripotent stem cells derived from patients with ornithine-δ-aminotransferase (OAT) deficiency |
| 9.50 – 10.10 | Birgit Veldman (UMC Utrecht), A#39 SGLT2 treatment in a patient with G6PC3 deficiency resulted in first-case recovery of thrombocytopenia, requiring gradual reduction of G-CSF treatment |
| 10.15 – 11.00 | Keynote speaker: Prof. Maria Falkenberg Topic: Inherited metabolic diseases Title: Mitochondrial DNA Maintenance: Understanding the Molecular Consequences of POLG Mutations of tumors and tryptophan University of Gothenburg, Sweden |
| 11.00 – 11.30 | Coffee break |
| Session 4 | |
| 11.30 – 11.50 | Evelien Peeters (Ghent University), A#27 Targeting the amino acid response pathway as defense against multiple aggressive cancer types |
| 11.50 – 12.10 | Merve Erdem (University Hospital RWTH Aachen), A#4 Carbohydrate-restricted diets have varying effects on the liver cancer progression in mice |
| 12.15 – 13.00 | Keynote speaker: Prof. Christiane Opitz Topic: Cancer metabolism Title: Of tumors and tryptophan German Cancer Research Center, DKFZ, Heidelberg, Germany |
| 13.00 – 14.00 | Lunch |
| Session 5 | |
| 14.00 – 14.20 | Jelle Huijts (Vrije Universiteit Amsterdam), A# Carbohydrate-restricted diets have varying effects on the liver cancer progression in mice |
| 14.20 – 14.40 | Esther Homan (UMC Groningen), A#15 One-carbon and NAD+ metabolic fluxes in an ex vivo precision-cut liver slice model for Glycogen Storage Disease type I |
| 14.40 – 15.00 | Moyan Liu (Amsterdam UMC), A#23 The Natural Metabolite 6-halo-tryptophan Ameliorates Adiposity in vivo and Promotes Lipid Catabolism |
| 15.00 – 15.45 | Keynote speaker: Prof. Javier Gonzales Topic: Nutrition and metabolism Title: Dietary carbohydrates and human metabolism – interactions with physical activity University of Bath, UK |
| 15.45 – 16.45 | Final remarks, conference evaluation and prize |