Dutch Translational Metabolism Conference 30-31st of May 2024
Hotel de Wageningsche Berg, Wageningen, The Netherlands

Day 130th of May, 2024
10:00 – 10.30Registration and coffee
10.30 – 10.45 Opening remarks
 Session 1
10.45 – 11.05Patrick van der Zande (Wageningen University), A#37

Weight cycling modifies the visceral adipose tissue and liver immune landscape without impacting whole-body insulin resistance in mice
11.05 – 11.25Fenne Verheijen (Utrecht UMC), A#40

Deciphering a tolerogenic diet; Is glutamate a key nutrient for tolerogenic dendritic cell functionality?
11.25 – 11.45Tobias Ackermann (CRUK Scotland Institute), A#1

Paracrine secretion of mono-unsaturated fatty acids prevents ferroptosis in triple-negative breast cancer and reveals selenocysteine synthesis dependency for lung metastasis
11.45 – 12.30Keynote speaker: Prof. Luke O’Neill

Topic: Immunometabolism
Title: A break in mitochondrial endosymbiosis as a basis for inflammatory diseases

Trinity College Dublin, Ireland
12.30 – 13.00Lunch
 Session 2
13.30 – 13.50Evi Koene (Maastricht UMC), A#21

Pharmacological inhibition of fructose metabolism reduces liver fat and improves insulin sensitivity in participants with MASLD
13.50– 14.10Jamie van der Vaart (Leiden UMC), A#36

Mitochondrial uncoupling with BAM15 prevents weight gain, lowers plasma cholesterol and attenuates atherosclerosis development in APOE*3-Leiden.CETP mice
14.10 – 14.55Keynote speaker: Prof. Bart Deplancke

Topic: Adipose biology
Title: Deconstructing adipose tissue plasticity, one cell at a time

EPFL, Switzerland
14.55 – 15.10Sponsor pitches
Masterclass & poster presentations
15.30 – 16.30Masterclass – Science Communication

Guest speakers:
– Martine Kamsma (Nutrition and Health Editor at NRC media)
– Jayson & Suzanne (Hosts of “The Struggling Scientists Podcast”)
– Eileen Daniels (Science communicator and research advisor in the field of medicine and natural sciences)
16:45 – 17:006 selected poster pitch presentations

Dandan Wu (Amsterdam University)
Xiaomeng Zhang (Amsterdam UMC)
Ruiqi Xiao (University of Groningen)
Anouk Gijbels (Wageningen University)
Froukje Vanweert (Maastricht University)
Demi Rijlaarsdam (Utrecht University)
17:00 – 18:00Poster session 1
18:15 – 19:15Poster session 2

19:15 –21.00Dinner
 21.00 –Evening program: PubQuiz
Day 231st of May, 2024
7.30 – 8.15Boot camp
8.30 – 9.30Breakfast
 Session 3
9.30 – 9.50Berith Balfoort (Amsterdam UMC), A#2

Altered mitochondrial function in induced pluripotent stem cells derived from patients with ornithine-δ-aminotransferase (OAT) deficiency
9.50 – 10.10 Birgit Veldman (UMC Utrecht), A#39

SGLT2 treatment in a patient with G6PC3 deficiency resulted in first-case recovery of thrombocytopenia, requiring gradual reduction of G-CSF treatment
10.15 – 11.00Keynote speaker: Prof. Maria Falkenberg

Topic: Inherited metabolic diseases
Title: Molecular consequences of POLG mutations and new avenues of treatment

University of Gothenburg, Sweden
11.00 – 11.30Coffee break
 Session 4
11.30 – 11.50Evelien Peeters (Ghent University), A#27

Targeting the amino acid response pathway as defense against multiple aggressive cancer types
11.50 – 12.10Merve Erdem (University Hospital RWTH Aachen), A#4

Carbohydrate-restricted diets have varying effects on the liver cancer progression in mice
12.15 – 13.00Keynote speaker: Prof. Christiane Opitz

Topic: Cancer metabolism
Title: Of tumors and tryptophan

German Cancer Research Center, DKFZ, Heidelberg, Germany
13.00 – 14.00Lunch
 Session 5
14.00 – 14.20 Jelle Huijts (Vrije Universiteit Amsterdam), A#16

Glut4 translocation during acute aerobic exercise in type 1 diabetes mellitus
14.20 – 14.40 Esther Homan (UMC Groningen), A#15

One-carbon and NAD+ metabolic fluxes in an ex vivo precision-cut liver slice model for Glycogen Storage Disease type I
14.40 – 15.00Moyan Liu (Amsterdam UMC), A#23

The Natural Metabolite 6-halo-tryptophan Ameliorates Adiposity in vivo and Promotes Lipid Catabolism
15.00 – 15.45Keynote speaker: Prof. Javier Gonzales

Topic: Nutrition and metabolism
Title: Dietary carbohydrates and human metabolism – interactions with physical activity

University of Bath, UK
15.45 – 16.45Final remarks, conference evaluation and prize