Dutch Translational Metabolism Conference
13-14th of June 2022
Hotel de Wageningsche Berg, Wageningen, The Netherlands

Themes of the conference:

  • Cellular and molecular metabolism
  • Systemic metabolism and inter-organ communication
  • Lifestyle interventions
  • Circadian Biology
  • Drug discovery and therapeutics promoting energy metabolism
  • Innovative methods for metabolic research
Day 113 June, 2022
9.30 – 10.30Registration and coffee
10.30 – 10.45 Opening remarks
 Session 1
10.45 – 11.30 Keynote speaker: Prof. Kei Sakamoto
(University of Copenhagen) 
Old and new insights into the role and therapeutic potential of the metabolic master AMPK”
11.30 – 11.50 Selected speaker: Judith de Jong
(UMC Utrecht)
The effect of acetate on intestinal maturation in prevention of necrotizing enterocolitis”
11.50 – 12.10 Selected speaker: Xi Qi
(Wageningen University)
Disruption of sarcoplasmic reticulum-mitochondrial contacts underlies contractile dysfunction in experimental and human atrial fibrillation: a key role of mitofusin 2”
12.10 – 12.30Selected speaker: Jiske Tiersma
(UMC Groningen)
Targeting glucose metabolism through inhibition of pyruvate dehydrogenase kinase to improve response to immune-checkpoint inhibition in melanoma”
12.30 – 13:30Lunch
 Session 2
13.30 – 13.50Selected speaker: Jayron Habibe
(Amsterdam UMC)
FHL2 in mice and human pancreatic beta-cells negatively affects insulin secretion”
13.50– 14.10Selected speaker: Cristy Verzijl
(UMC Groningen)
A novel role for GalNAc-T2 dependent glycosylation in energy homeostasis”
14.10 – 14.30Selected speaker: Sten van Beek
(Maastricht UMC)
Treatment with the beta2-adrenergic agonist clenbuterol promotes insulin-stimulated skeletal muscle glucose uptake in healthy males”
14.30 – 15.15Keynote speaker: Dr. Anja Zeigerer 
(Helmholtz Centrum) 
Intracellular transport in systemic energy homeostasis and diabetes”
15.15 – 16.00Break and check-in
16.00 – 17.00Career trajectory masterclass with keynote speakers
17.00 – 17.45Poster pitch presentations:
Adam Sellers, Maastricht UMC
Charlotte Andriessen, Maastricht UMC
Irena Muffels, UMC Utrecht
Gautam Kok, UMC Utrecht
Moritz Eggelbusch, Amsterdam UMC
Signe Mosegaard Nielsen, Amsterdam UMC
Milena Schönke, Leiden UMC
Maria Colman, UMC Utrecht
Jeroen van der Velde, Leiden UMC
Martijn Rutten, UMC Groningen
17.45 – 21.00Dinner and poster session
21.00 – Evening program
Day 214 June, 2022
7.30 – 8.15Boot camp
8.30 – 9.30Breakfast
 Session 3
9.30 – 9.50Selected speaker: Anouk Gijbels
(Wageningen U)
“Precision nutrition by targeting diets according to tissue-specific insulin resistance phenotypes improves markers of cardiometabolic disease risk: the PERSON study”
9.50 – 10.10 Selected speaker: Alex Schuurman
(Amsterdam UMC)
The shifting lipidomic landscape of monocytes and neutrophils during pneumonia”
10.15 – 11.00Keynote speaker: Dr. Giles Yeo 
(University of Cambridge)
“Is obesity a choice?”
11.00 – 11.30Coffee break
 Session 4
11.30 – 11.50Selected speaker: Amee Buziau
(Maastricht UMC)
A common variant in the ketohexokinase gene is associated with fructosuria and cardiometabolic outcomes”
11.50 – 12.10Selected speaker: Elise Ferreira
(Amsterdam UMC)
Diagnosing, Discarding or De-VUSsing: a practical guide to (un)targeted metabolomics as variant-transcending functional tests”
12.15 – 13.00 Keynote speaker: Prof. Anu Suomalainen Wartiovaara
(University of Helsinki)
“Metabolic modifier therapies and cell-specific stress responses: complex physiology of mitochondrial disease”
13.00 – 14.00Lunch
 Session 5
14.00 – 14.20 Selected speaker: Froukje Vanweert
(Maastricht UMC)
“Lowering branched-chain amino acid levels in patients type 2 diabetes by sodium-phenylbutyrate improves insulin sensitivity”
14.20 – 14.40 Selected speaker: Rodrigo Mancilla
(Maastricht UMC)
“High intensity interval training improves whole-body insulin sensitivity and skeletal muscle oxidative capacity and favorably affects hepatic fat storage”
14.45 – 15.30 Keynote speaker: Prof. Lora Heisler
(University of Aberdeen)
“Targeting the brain to improve obesity and type 2 diabetes”
15.30 – 16.00Final remarks, Conference evaluation, and Prizes