Seminar 3: April 1st

On April 1st, from 16:00-17:15, our keynote speaker will be Prof. Dr. Leanne Hodson of Oxford University in the UK. She will be joined by Dr. Joanne Hoogerland of the Institut Pasteur de Lille and UMCG.

Prof. Dr. Leanne Hodson (University of Oxford)

Prof. Leanne Hodson received her PhD in Human Nutrition from the University of Otago, New Zealand. She was awarded the Girdlers-Health Research Council of New Zealand Career Development Award to come and work with Professors Keith Frayn and Fredrik Karpe, University of Oxford. Over the course of her time in Oxford Leanne has been awarded British Heart Foundation (BHF) Intermediate and Senior Research Fellowships and is currently in the process of renewing the latter.  She is Professor of Metabolic Physiology and her research interests focus on the alterations in metabolism with nutritional state and substrates (e.g. sugars, fatty acids) along with the associated metabolic consequences of obesity. The groups current focus is on understanding liver fat metabolism, as perturbations in this have the potential to impact widely on metabolic health.  We perform whole body human physiological studies to understand the metabolic integration between tissues. Her group routinely uses stable-isotope metabolic tracer methodologies to probe metabolism in the following models: in vivo human, ex situ liver and in vitro cellular.  Leanne’s work enables interdisciplinary collaborations covering a number of areas including metabolism and physiology, nutrition, cardiovascular disease, hepatology, diabetes, and liver transplantation.

Dr. Joanne Hoogerland (Institut Pasteur de Lille & UMC Groningen)

”Hypoglycemia aggravates dyslipidemia in GSD Ia via enhanced adipocyte lipolysis and impaired VLDL catabolism’

Joanne Hoogerland started her PhD in 2015 at the department of Pediatrics, section Molecular Metabolism & Nutrition, at UMCG, under supervision of dr. M.H. Oosterveer and prof. dr. F. Kuipers. Her PhD project entitled ‘Altered lipid and bile acid metabolism in Glycogen Storage Disease type Ia: pathophysiological mechanisms and therapeutic opportunities’ was successfully defended in 2020. She is currently working as a post-doctoral researcher at the Institut Pasteur de Lille, France, under supervision of prof. dr. B. Staels and dr. D. Dombrowicz. The aim of her project is to establish the role of bile acids in the modulation of the adaptive immune system and its contribution to obesity-induced inflammation.