Program

Dutch Translational Metabolism Conference 27-28th of May 2025
Hotel de Wageningsche Berg, Wageningen, The Netherlands

Day 1	27th of May, 2025
10:00–10.25	Registration and coffee
10.30–10.45	Opening remarks
	Session 1 Brain Storm: Neuroendocrinology
10.45–11.05	Abstract presentation 1 – Inge van der Stelt (Wageningen University), A#44 Absence of mitochondrial nicotinamide nucleotide transhydrogenase triggers glucocorticoid-associated gene expression in the hippocampus of infant mice
11.05–11.25	Abstract presentation 2 – Dzhansel Hashim (Maastricht University), A#15 Acute effects of cold exposure with shivering, at two intensities, on 24-hour glucose profiles of volunteers with prediabetes and type 2 diabetes
11.25–11.45	Abstract presentation 3 – Jamie van der Vaart (Leiden UMC), A#45 Long-acting glucagon receptor agonism increases circulating triglyceride levels in diet-induced obese mice
11.45–12.30	Keynote speaker: Prof. Dr. Jens Brüning Max Planck Institute, Cologne, Germany
12.30–13.25	Lunch
	Session 2 The Beat Goes On: Cardiovascular Health
13.30–13.50	Abstract presentation 4 – Yun Hu (Wageningen University), A#18 Nicotinamide riboside prevents ageing-related decline in lipid oxidation and cardiac diastolic function in mice
13.50–14.10	Abstract presentation 5 – Yan Fang (Wageningen University), A#11 A Metabolomics-Derived Med-score Linking Mediterranean Diet Adherence to Cardiometabolic Health
14.10–14.55	Keynote speaker: Prof. Dr. Christoph Maack Universitätklinikum Würzburg, Germany
14.55–15.10	Sponsor pitches, Akoya Biosciences, PHC Europe, Sable Systems Europe
15.10– 15.25	Coffee Break
15.30–16.30	Guided walking tour/ Free hour
16.45–17.00	6 selected poster pitch presentations Pitch 1 – Brian Chen (Vrije Universiteit) #6 Untargeted Metabolomics Analysis in Skeletal Muscle: Metabolite Alterations in Skeletal Muscle of Long COVID Patients Pitch 2 – Esther Homan (UMC Groningen) #16 One-carbon and NAD+ metabolic fluxes in an ex vivo precision-cut liver slice model for Glycogen Storage Disease type I Pitch 3 – Liangyu Hu (Wageningen University) #17 The dual role of vitamin B3 nicotinamide in cardiac function and arrhythmogenesis: Mind the dose! Pitch 4 – Marit Kotte (Maastricht University) #22 The Impact of Acute AM vs. PM Exercise on Nocturnal Energy and Substrate Metabolism in Individuals at Risk of Developing Type 2 Diabetes Pitch 5 – Vera Spek (Amsterdam UMC) #40 Metabolomic Signatures of Aging and Lifestyle Interventions in Whole Blood Pitch 6 – Kasper Vinten (Amsterdam UMC) #48 Comparative analysis reveals profound transcriptomic and metabolic differences between reduced and oxidized NAD+ precursors in cultured hepatocytes
17.15–18.15	Poster session 1: even numbers
18.30–19.30	Poster session 2: odd numbers
19.30–21.00	Dinner
21.00 –	Evening program
Day 2	28th of May, 2025
8.30–9.25	Breakfast
	Session 3 Play Together & Stay Together: Organ Crosstalk
9.30–9.50	Abstract presentation 6 – Ivo Habets (Maastricht UMC), A#14 Natural daylight during office hours improves glucose control and whole-body substrate metabolism, and impacts the blood multi-omic signature in type 2 diabetes
9.50–10.10	Abstract presentation 7 – Weisha Li (Amsterdam UMC), A#25 Acyl chain length of lipids mark aging, disease progression, and intervention
10.10–10.55	Keynote speaker: Dr. Amalia Gastaldelli Institute of Clinical physiology of CNR, Pisa, Italy
11.00–11.25	Coffee break
	Session 4 Gut Feelings: Microbiome & Metabolism
11.30–11.50	Abstract presentation 8 – Katina Hulme (Amsterdam UMC), A#19 A history of obesity increases the severity of influenza virus infection via the induction of innate immune training
11.50–12.10	Abstract presentation 9 – Mijra Koning (Amsterdam UMC), A#21 Induction of liver injury in metabolic dysfunction associated steatotic liver disease by microbial metabolite 3-4-Hydroxyphenyllactate through hepatic cellular senescence
12.10– 12.30	Abstract presentation 10 – Xiaoxu Li (École Polytechnique Fédérale de Lausanne), A#27 Genetic mapping of lifespan and mitochondrial stress response in C. elegans
12.30–13.15	Keynote speaker: Karine Clément Pitié-Salpêtrière Hospital and Sorbonne University, Paris, France Gut microbiome and Cardiometabolic diseases: Lessons Learned from the EU-MetaCardis Project
13.15–14.15	Lunch
	Session 5 The Future is Here: Innovation, Models, AI
14.20–14.40	Abstract presentation 11 – Pip van Lier (Maastricht University), A#46 Prolonged β2-agonist treatment enhances muscle-specific glucose uptake in individuals with overweight and obesity: a randomized placebo-controlled trial
14.40–15.00	Abstract presentation 12 – Maria Matamala Montoya (Utrecht University), A#30 Metabolic flux in the Multiple Myeloma Tumor Microenvironment: The Impact of Interleukin-6
15.00–15.45	Keynote speaker: Dr. Theodore Alexandrov University of California San Diego, USA
15.45– 16.15	Prizes, conferences evaluation, final remarks