Seminar 1: February 1st

The first online seminar of 2024 will take place on February 1st from 16:00-17:00. The keynote speaker will be Professor Romain Barrès from the center for Basic Metabolic Research (CBMR), University of Copenhagen. He will be joined by Ricky Siebeler from Amsterdam UMC.

“Epigenetic rewiring of skeletal muscle after exercise training”

Romain Barrès is Director of Research at the Institute of Molecular and Cellular Pharmacology (IPMC) CNRS/Université Côte d’Azur in France and Professor at the Center for Basic Metabolic Resear (CBMR), University of Copenhagen, Denmark. He obtained his Bachelor in Physiology from the University of Toulouse III (France), a Master and PhD in Molecular Biology from the University of Nice Côte d’Azur, France, and conducted his postdoctoral studies at the Karolinska Institutet in Stockholm. He worked as a Lecturer at the University of New South Wales in Sydney before he returned to establish his group at the CBMR in 2010. Prof. Barrès is currently Head of the Gametic Epigenetic Consortium against Obesity (GECKO).

His research is focused on the understanding of lifestyle influences on the predisposition to develop metabolic diseases later in life. His group notably developed expertise in the field of epigenetic inheritance and led seminal work addressing the effect of preconceptional factors on the epigenome of spermatozoa and the metabolic phenotype of the offspring. 

“The histone demethylase KDM3A modulates the pro-inflammatory phenotype of macrophages in atherosclerosis”

Ricky Siebeler is a PhD student specializing in the epigenetic regulation of macrophages in the context of atherosclerosis. Currently, he works under the guidance of Prof. Menno de Winther and Dr. Marten Hoeksema at the Amsterdam UMC. His primary focus lies in characterizing novel epigenetic regulators of interferon signaling in macrophages, with the overarching goal of understanding how these regulators can be targeted to mitigate inflammatory responses in atherosclerosis.

Ricky obtained his Bachelor’s and Master’s degrees in Nutrition and Health, specializing in Molecular Nutrition and Toxicology at Wageningen University & Research. For his first master internship he worked on a project at the Department of Nutrition, Metabolism, and Genomics in Wageningen, focusing on the role of mitochondrial fatty acid synthesis in macrophage activation. Subsequently, his second internship at the Department of Medicine, Leiden, focused on lipid metabolism and chronobiology in atherosclerosis.  Combining interests from both disciplines, Ricky’s is excited to build upon his prior experiences in his current research.